Evaluation of different extraction method for the isolation of cimetidine and ranitidine from human plasma for HPLC analysis

• Main Authors: Helal Uddin, A.B.M., Awang, Mohamed, Rahman, Md. Mokhlesur, Khan, Umeed Ali
• Format: Proceeding Paper
• Language: English; English
• Published: 2012
• Subjects: QD Chemistry; RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/32317/1/PROCEEDING_COVER.pdf; http://irep.iium.edu.my/32317/2/ID_197_-_pp_669-673_ABM_Helal_Uddin.pdf; http://irep.iium.edu.my/32317/

Cimetidine and ranitidine are classified as the H2-receptor antagonists (H2 antagonist). These classes of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H2 antagonists are widely used in the treatment of gastro oesophag...