Application of filtration blocking models to describe fouling and transmission of large plasmids DNA in sterile filtration
Sterile filtration is considered as a final step in processing pharmaceutical grade plasmid DNA. During the development of the filtration process, fundamental understanding on the mechanism of fouling is critical to improve filtration operations. The mechanism of fouling of pQR150 (20 kb) and pGEc4...
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Main Authors: | Salim, Affaro Affandy, Eli, Keshavarz-Moore, Henk, Versteeg |
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Format: | Article |
Language: | English |
Published: |
ELSEVIER
2013
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Subjects: | |
Online Access: | http://irep.iium.edu.my/29820/1/A.Affandy-2013.pdf http://irep.iium.edu.my/29820/ http://dx.doi.org/10.1016/j.memsci.2013.02.055 |
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