Microarray and quantitative PCR analysis of gene expression profiles in response to treatment with tomato leaf extract in MCF-7 breast cancer cells

• Main Authors: Amid, Azura, Wan Chik, Wan Dalila, Jamal, Parveen, Hashim, Yumi Zuhanis Has-Yun
• Format: Article
• Language: English
• Published: National Cancer Center, Korea. 2013
• Subjects: R Medicine (General); RC0254 Neoplasms. Tumors. Oncology (including Cancer)
• Online Access: http://irep.iium.edu.my/29473/1/Microarray_TLE.pdf; http://irep.iium.edu.my/29473/; http://www.apocpcontrol.org/page/apjcp_issues_view.php?sid=Entrez:PubMed&id=pmid:23464452&key=2012.13.12.6319

We previously found cytotoxic effects of tomato leaf extract (TLE) on the MCF-7 breast cancer cell line. The aim of this study was to ascertain the molecular mechanisms associated with the usage of TLE as an anticancer agent by microarray analysis using mRNA from MCF-7 breast cancer cells after tr...