Potent α-glucosidase and α-amylase inhibitory activities of standardized 50% ethanolic extracts and sinensetin from Orthosiphon stamineus Benth as anti-diabetic mechanism

• Main Authors: Mohamed, Elsnoussi Ali Hussin, Siddiqui, Mohammad Jamshed Ahmad, Lee, Fung Ang, Sadikun, Amirin, Sue, Hay Chan, Soo , Choon Tan, Asmawi, Mohd Zaini, Mun , Fei Yam
• Format: Article
• Language: English
• Published: BioMed Central 2012
• Subjects: QD Chemistry
• Online Access: http://irep.iium.edu.my/28353/1/BMC_CAM-2012.pdf; http://irep.iium.edu.my/28353/

Background: In the present study, we tested a 50% ethanolic extract of Orthosiphon stamineus plants and its isolated bioactive compound with respect to their α-glucosidase and α-amylase inhibitory activities. Methods: Bioactive flavonoid sinensetin was isolated from 50% ethanolic extract of Orthosi...