Stereoselective preparations of epoxy-, fluoro- and related derivatives of ricinoleic acid and 13(S)-hydroxyoctadeca-9(Z),11(E)-dienoic acid

• Main Authors: Omar, Muhammad Nor, Hamilton, Richard J, Moynihan, Humphrey A
• Format: Article
• Language: English
• Published: ARKAT USA Inc 2003
• Subjects: QD Chemistry
• Online Access: http://irep.iium.edu.my/24437/1/Stereoselective_preparation_of_related_derivatives_of_ricinoleic_and_13S_HODE.pdf; http://irep.iium.edu.my/24437/; http://www.arkat-usa.org/about-arkat-usa/

Methyl ricinoleate 4 and methyl 13(S)-hydroxyoctadeca-9(Z),11(E)-dienoate 7 were subjected to epoxidation using mCPBA, or tert-butyl hydroperoxide in the presence of vanadyl acetylacetonate or titanium (IV) isopropoxide with D-(-)- or L-(+)-diisopropyl tartrate. Epoxidations using mCPBA gave equal q...