Prediction of anticancer activity of aliphatic nitrosoureas using quantum chemical quantitative structure activity relation (QSAR) methods

• Main Authors: Noorbatcha, Ibrahim Ali, Hamzah, F., Mohd. Salleh, Hamzah, Syed Osman Idid, Syed Zahir Idid
• Format: Article
• Language: English
• Published: Academic Journals 2011
• Subjects: TP Chemical technology
• Online Access: http://irep.iium.edu.my/14650/1/QSAR_AJB_2011_published.pdf; http://irep.iium.edu.my/14650/; http://www.academicjournals.org/ajb/PDF/pdf2011/16DecConf/Noorbatcha%20et%20al.pdf

Design and development of new anticancer drugs with low toxicity is a very challenging task and computer aided methods are being increasingly used to solve this problem. In this study, we investigated the anticancer activity of aliphatic nitrosoureas using quantum chemical quantitative structure...