Chronic Organophosphate Pesticide Exposure and Coronary Artery disease : finding a bridge

• Main Authors: Abdullah, Nor Zamzila, Ishaka, Aminu, Samsuddin, Niza, Mohd Rus, Razman, Mohamed, Abdul Hadi
• Format: Conference or Workshop Item
• Language: English
• Published: 2011
• Subjects: RA1190 Toxicology; RB Pathology
• Online Access: http://irep.iium.edu.my/13579/1/IRIIE_2010_Organophosphate_%26_CAD.pdf; http://irep.iium.edu.my/13579/

Organophosphates (OPs) are commonly used as pesticides in agriculture. They are hydrolyzed by paraoxonase (PON1) which is a high density lipoprotein (HDL) associated enzyme known for its function to hydrolyze OPs into a relatively harmless substance. PON1 is also known to prevent atherosclerosis by...