Urine brilliance: urine TB LAM's role in challenging AIDS cases from LMIC's perspective

• Main Authors: Zainulabid, Ummu Afeera, Cheong, Xiong Khee, Hussin, Fara Rahidah, Periyasamy, Petrick
• Format: Article
• Language: English; English; English; English
• Published: Elsevier Ltd 2024
• Subjects: RC111 Infectious and Parasitic Diseases
• Online Access: http://irep.iium.edu.my/116264/18/116264_Urine%20brilliance%20Urine%20TB%20LAM%27s%20role%20in%20challenging%20AIDS%20cases%20from%20LMIC%27s%20perspective.pdf; http://irep.iium.edu.my/116264/1/116264_Slide%20presentation_Urine%20brilliance%20urine%20TB%20LAM%27s%20role%20in%20challenging.pdf; http://irep.iium.edu.my/116264/2/116264_Abstract_Urine%20brilliance%20urine%20TB%20LAM%27s%20role%20in%20challenging.pdf; http://irep.iium.edu.my/116264/3/116264_Certificate_Urine%20brilliance%20urine%20TB%20LAM%27s%20role%20in%20challenging.pdf; http://irep.iium.edu.my/116264/; https://www.sciencedirect.com/journal/cmi-communications/vol/1/issue/1/suppl/S

The identification of reliable markers for active tuberculosis (TB) diagnosis is pivotal, especially in challenging scenarios, particularly in low- and middle-income countries (LMICs), where co-infections, notably among individuals with AIDS, pose significant diagnostic challenges. Lipoarabinomannan (LAM), an immunogenic virulence factor released from metabolically active or degrading mycobacteria, presents a promising avenue for overcoming these hurdles. In this study, we present a case series that underscores the intricacies of TB diagnosis, specifically focusing on individuals co-infected with AIDS in LMICs.