Dosing, toxicity and drug concentrations for ganciclovir/valganciclovir in preterm and low birthweight Infants treated for cytomegalovirus

• Main Authors: Abu Bakar, Asrar, Helen, Payne, Neil, Tickner, Muhd Helmi, Muhd Alwi, Jacobs, Tom G, Hermione, Lyall
• Format: Article
• Language: English
• Published: Wolters Kluwer Health, Inc. 2024
• Subjects: RJ251 Newborn infants. Neonatology; RJ254 Disease and abnormalities; RJ370 Disease of children; RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/115860/7/115860_Dosing%2C%20toxicity%20and%20drug%20concentrations%20for%20GanciclovirValganciclovir.pdf; http://irep.iium.edu.my/115860/; https://journals.lww.com/pidj/fulltext/9900/dosing,_toxicity_and_drug_concentrations_for.1087.aspx

Background: There is a lack of data regarding suitable dosage when administering intravenous ganciclovir (GCV) or oral valganciclovir (valGCV) to preterm and low birthweight infants with cytomegalovirus (CMV) disease. Methods: Data were collected for infants born before 32 weeks gestation and...