Three-dimensional culture model of urothelial carcinoma cell lines: current advances, challenges and future perspective

• Main Authors: Mansor, Siti Farizan, Tengku Zakaria, Tengku Muhamad Faris Syafiq, Yahaya, Badrul Hisham
• Format: Article
• Language: English
• Published: BioMedPress 2024
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/115733/1/115733_Three-dimensional%20culture%20model.pdf; http://irep.iium.edu.my/115733/; http://bmrat.org/index.php/BMRAT/article/view/925

Despite the high number of cases reported, studies describing the pathogenesis of urothelial carcinoma (UC) remain limited. This is due to insufficient in vivo models that can accurately recapitulate the pathogenesis of UC recurrence and elucidate the involvement of the tumour microenvironment (TME)...