Ethnomedicine: extraction of acacia auriculiformis leaves and phenolic compounds screening for pharmacological uses
Acacia auriculiformis, sometimes known as akasia kuning by the Malay, is a globally widespread tree with a diverse variety of therapeutic properties. Traditionally, it has been used to address a range of medicinal issues, including the use of the root to alleviate aches, pains, and sore eyes and th...
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| Main Authors: | , , , , |
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| Format: | Proceeding Paper |
| Language: | English English |
| Published: |
Fakultas Perikanan dan Kelautan, Universitas Riau
2024
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/114463/1/ABSTRACT3.pdf http://irep.iium.edu.my/114463/13/114463_Ethnomedicine%20extraction%20of%20acacia%20auriculiformis%20leaves.pdf http://irep.iium.edu.my/114463/ |
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| Summary: | Acacia auriculiformis, sometimes known as akasia kuning by the Malay, is a globally widespread tree with a diverse variety of therapeutic properties. Traditionally, it has been used to
address a range of medicinal issues, including the use of the root to alleviate aches, pains, and sore eyes and the use of the bark to cure rheumatism. The phytochemicals found in different portions of plants have significant potential to function as medicinal remedies for various ailments and
exhibit pharmacological effects. However, there is a lack of studies reported on A. auriculiformis leaf. This research aims to examine the phenolic compounds and determine the antibacterial activity of the leaf extract from A. auriculiformis. The leaf extract of A. auriculiformis was extracted with aqueous extraction before being re-extracted using different solvent polarities:petroleum ether, ethyl acetate, and butanol. Then, the extract was subjected to chromatographic
analysis to determine its functional group using FT-IR and its phenolic content using HPLC. The antibacterial activity was assessed using the disc diffusion technique. The analysis revealed the existence of an aliphatic hydrocarbon at a wavelength of 2927.49 cm1 in A. auriculiformis. The
leaf extract had a total phenolic content of 409.18 μg GAE/g DW, and four phenolic acids were identified: 4- Hydroxybenzoic acid, Caffeic acid, trans-p-Coumaric acid, and Vanillic acid. The A. auriculiformis leaf extract exhibited high antibacterial activity, as evidenced by the presence of
inhibition zones measuring between 3 and 10 mm for all investigated bacterial pathogens (S. aureus, S. epidermidis, E. coli, MRSA, and P. aeruginosa). Overall, the leaves of A. auriculiformis demonstrate promise as a possible source of phenolic compounds and exhibit significant antibacterial activity, indicating their potential use in producing these compounds. |
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