Study on Malay traditional medicine ingredients using selected Zingiberaceae species for carotenoid, antioxidant and antimicrobial properties and activities

• Main Authors: Othman, Rashidi, Abu Bakar, Ainaa Eliah, Mohd Latiff, Nur Hanie, Wan Sulaiman, Wan Syibrah Hanisah, Ramya, Razanah, Mohd Hatta, Farah Ayuni
• Format: Proceeding Paper
• Language: English; English
• Published: Fakultas Perikanan dan Kelautan, Universitas Riau 2024
• Subjects: RS Pharmacy and materia medica; S Agriculture (General); TP248.13 Biotechnology; TP372.6 Halal food industry; TP934 Paints, pigments, varnishes, etc
• Online Access: http://irep.iium.edu.my/114462/13/114462_Study%20on%20Malay%20Traditional%20Medicine%20Ingredients%20Using%20Selected%20Zingiberaceae%20Species%20for%20Carotenoid%20Antioxidant%20and%20Antimicrobial%20Properties%20and%20Activities_EHMAP2.pdf; http://irep.iium.edu.my/114462/14/114462_Study%20on%20Malay%20Traditional%20Medicine%20Ingredients%20Using%20Selected%20Zingiberaceae%20Species%20for%20Carotenoid%20Antioxidant%20and%20Antimicrobial%20Properties%20and%20Activities_Abstract.pdf; http://irep.iium.edu.my/114462/

The traditional uses of the family Zingiberaceae have a long history and include everything from folk medicine to culinary applications. Numerous ginger species have been the subject of numerous phytochemical, pharmacological, and molecular studies worldwide. The identification of novel bioactive molecules with a variety of bioactivities, including antioxidant, antiviral, antibacterial, and anti-inflammation activities, has boosted interest in its therapeutic qualities. Therefore, the ultimate aim of this study is to establish a scientific basis in supporting the claims of the therapeutic effects of the Malay traditional medicinal plants for a better understanding of preserving, conserving and utilising the traditional knowledge to sustain the Malay cultures and its identity for future reference. HPLC analysis was used to quantify carotenoids in 12 ginger species whereas DPPH and MIC tests were used to measure the antioxidant properties and antimicrobial activities. The results established that Kunyit (C. longa), a dark orange-fleshed rhizome, was found to have the highest carotenoid content (578.38 ± 6.37 μg/g DW) and demonstrated substantially the highest DPPH scavenging activity of 98.43% inhibition at the concentration of 1 mg/ml. The MIC antimicrobial test established that the highest antimicrobial inhibitory activity was obtained from the extract of Temu emas (C. heyneana) which recorded the lowest MIC values ranged from 2 to 3 μg/μl against all five pathogenic microorganisms. These findings also highlighted that different extraction method and rhizome flesh colour can influence the antimicrobial activities and DPPH scavenging activity.