Unveiling the impact of Chlorella vulgaris supplementation on liver metabolisms of aged rats − A preclinical study

• Main Authors: Ogechi Ekeuku, Sophia, Zainul Azlan, Nurhazirah, Mohd Yusof, Yasmin Anum, Tan, Jen Kit, Makpol, Suzana
• Format: Article
• Language: English; English
• Published: Elsevier 2024
• Subjects: Q Science (General)
• Online Access: http://irep.iium.edu.my/114213/7/114213_%20Unveiling%20the%20impact%20of%20Chlorella.pdf; http://irep.iium.edu.my/114213/8/114213_%20Unveiling%20the%20impact%20of%20Chlorella_Scopus.pdf; http://irep.iium.edu.my/114213/; https://pdf.sciencedirectassets.com/277412/1-s2.0-S1756464624X00092/1-s2.0-S1756464624003852/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEIP%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJHMEUCIE6OWpHsDnIhC7%2B%2Fi%2Fz6T4cHRXnTGN2czVrL6TR33iUAAiEAktFh5fe3gNRzbyzFpZEfqGgh4ms3J8g3vf7HV%2BX%2BudEquwUIm%2F%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FARAFGgwwNTkwMDM1NDY4NjUiDF%2FZ7MqPFF%2F8leOf1yqPBU0eWt7Qm%2BNexgltLk46Pdra7QSPZbmqnadPWuCVmHLpEwWXJsCQ90qntKuK4g%2BJEYI8OLfyOavdVVkzXXK3CCGKvJI2IamDyI8CQSlhCMlq90KF%2Fyq5j1Qp1wqsNFL0G3fegq%2BYG8fhskH7H7OKb8jP7NfS8Z7WH9EbpKFrxXn2wUYmQJPhQahk4rf3aXfjtNxDSiGvHD6pzf3Sdvxf83wOEzYx9tWADMGqoudT%2FOOydmgTy%2Bh%2FLIeg6vxTnzF1kJe1wT6uSVEto4jAefV9bermHW4Kw2Ajnk30PGbZ6UC8LdzODiOZZnZ8MLijezUXZ3jb2l4maD%2FdYM6F%2FWGLTYUWYcu7a%2FawyndAXT2vivuu8Gdv43q85lRZqzh8GLXvnMzsCg5Id3PG2WUcVULsQbgR6yl454EptUxFU5o2yDDG%2FdYmlIu9uru3HKUgqchMa3i%2BLn2gnCXPwwXPhGLI17p43dKtX5vb5SVIlCGp6OIK9lXA0YXP8Y%2BIPVNuKHjIsKU%2FOp7G8CeleTj06oRlCgsc%2BmQRSFglsntYp%2FxVoiAKNWF8enGFinHimNl4QdxqbQ037v5Oonmyk%2FvvzZG7uD%2FyCVXV9YQkqHz5rIWwKKnrIgPNqSDtdC1pXwWubAn6cz5NAdANFSdoOyTuYAquhNaI1m2erz1rbRjgLilj56nzissEscsMFCy%2Bzdhg3CsChPukM7A%2BOsAeX%2FdpvKcbnCD8hF9E9ufQR1zewL2XbqqRGgxjk1EGDVUfF1S7NORayhqbsWVfaGQcSWmFRbKD4NwZZzAddehZ88986DtPUMZAcwWFx5jabDGUU14AbSUHLHVDOVTdBCXUC0V16VcjhEeO9FPwVDps9ZNjNWo4RDAw87zUtgY6sQH%2FyOH3HifRy%2FpivRZvvbN65MlLRf39fUs%2FjF90DkrdOsw9fw69amZU8BBZz4PoMph8%2BbtF7KKrJmM%2FcOEAD5Gbj0cdDTFKZaCUo1%2BCZ1LEoK0BQR%2BDBFNQ%2Bnnlq9SeuYN9egM%2BRcBnHjYWNgum7aOM0ky4laRgzuDhGcWEaSdmZ1tx9qWpca11lnmfkC9%2BNkN%2Fqcz9iaubPD0HfEgpK3jifOMPyZrKgbmNLeXia3qpFqE%3D&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Date=20240902T032811Z&X-Amz-SignedHeaders=host&X-Amz-Expires=300&X-Amz-Credential=ASIAQ3PHCVTY7RONZZAB%2F20240902%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Signature=ea60834bf1e52b6e8b5289b403006cfe209525f6bee80c6cb48489e949aef8c2&hash=53ed7c0de8711f4d9c9a1419e4bfa71dcbbf44063ec6c455b71dcd2b8ff61596&host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&pii=S1756464624003852&tid=spdf-5b1f685c-545a-4bd6-a3c1-6c10f04acf60&sid=020b2b9354847243732b2348e745fd01e16egxrqb&type=client&tsoh=d3d3LnNjaWVuY2VkaXJlY3QuY29t&ua=171f5d01040e565a575656&rr=8bca68938a5b6bc9&cc=my; https://doi.org/10.1016/j.jff.2024.106383

Chlorella vulgaris is renowned for its rich nutritional composition and has been associated with various health benefits. This study aimed to look into the effect of CV on liver metabolomes and metabolic pathways in aged Sprague Dawley (SD) rats. Three and 21-month-old male SD rats were divided into...