Tamoxifen and residual tumor volume in postoperative nonfunctioning pituitary neuroendocrine tumors: a pilot study

• Main Authors: Haydar Ali Tajuddin, Amalina, Sukor, Norlela, Azizan, Elena Aisha, Kamaruddin, Nor Azmi, Omar, Ahmad Marzuki, Tan, Geok Chin, Mustangin, Muaatamarulain, Mohamed Mukari, Shahizon Azura, Alias, Azmi, Abd Latif, Kartikasalwah, Tay, Poh Sen, Kasim, Fauziah, Wan Ismail, Wan Ruza Iswati
• Format: Article
• Language: English
• Published: Japan Endocrine Society 2024
• Subjects: RC Internal medicine; RC254 Neoplasms. Tumors. Oncology (including Cancer); RC48.8 Rare diseases; RC648 Specialties of Internal Medicine-Diseases of The Endocrine Glands. Clinical Endocrinology; RC66 Clinical cases
• Online Access: http://irep.iium.edu.my/112637/1/112637_Tamoxifen%20and%20residual%20tumor%20volume.pdf; http://irep.iium.edu.my/112637/; https://doi.org/10.1507/endocrine.100.1_149

Selective anti-estrogen receptor modulators (SERMs) have been shown to reduce the size of pituitary tumors. However, their clinical effect on nonfunctioning pituitary neuroendocrine tumors (NF-PitNET) in humans has not yet been established. We conducted a randomized controlled trial of tamoxifen ver...