Evaluation on the potential of Ganoderma lucidum bioactive compounds as alpha-glucosidase enzyme inhibitor: a computational study

• Main Authors: Sharif, Mohd. Faez, Atan, Amirul Khairullah, Azizan, Nur Hafizah, Abdul Hamid, Azzmer Azzar, Ismail, Che Muhammad Khairul Hisyam, Mohd Aris, Mohd Shukri
• Format: Article
• Language: English; English
• Published: Faculty of Medicine and Health Sciences, University Putra Malaysia 2024
• Subjects: Q Science (General)
• Online Access: http://irep.iium.edu.my/111952/2/111952_Evaluation%20on%20the%20potential%20of%20Ganoderma.pdf; http://irep.iium.edu.my/111952/3/111952_Evaluation%20on%20the%20potential%20of%20Ganoderma_Scopus.pdf; http://irep.iium.edu.my/111952/; https://medic.upm.edu.my/jurnal_kami/volume_20_2024/mjmhs_vol20_no_2_march_2024-78509; https://doi.org/10.47836/mjmhs.20.2.23

Introduction: Computational simulation study was carried out on bioactive compounds of Ganoderma lucidum (G. lucidum). Methods: Molecular docking and molecular dynamics (MD) simulations were performed. The input files for protein and ligands were retrieved from Protein Data Bank (PDB) and PubChem da...