Analysis of impedance based sensor to discover the invasive nature of A549 lung cancer cell
Numerous studies have been conducted to investigate the effectiveness of impedancebased sensors in detecting the invasive behaviour of cancer cells, specifically through the use of Electric Cell-substrate Impedance Sensing (ECIS) methodology. However, the current equivalent circuit models used to...
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2024
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my.iium.irep.1116142024-04-03T07:22:00Z http://irep.iium.edu.my/111614/ Analysis of impedance based sensor to discover the invasive nature of A549 lung cancer cell Rashid, Muhammad Mahbubur Abd Razak, Mohamad Farhan Hasan, Tahsin Fuad TK452 Electric apparatus and materials. Electric circuits. Electric networks Numerous studies have been conducted to investigate the effectiveness of impedancebased sensors in detecting the invasive behaviour of cancer cells, specifically through the use of Electric Cell-substrate Impedance Sensing (ECIS) methodology. However, the current equivalent circuit models used to represent the invasive nature of cancer cells have limitations and inaccuracies, and there has been a lack of utilization of mathematical and data analysis software to better understand the growth and invasive behaviour of these cells. To address these gaps, this research aims to measure the impedance of A549 lung cancer cells, develop a simplified equivalent circuit model, and analyse the results using mathematical and data analysis software. The invasive behaviour of A549 cells will first be studied through impedance measurements, and then a circuit model will be designed and simulated using software tools to reveal the true invasive nature of these cells. Finally, rigorous mathematical analysis and the use of suitable data analysis software (such as Matlab Powergui and Simulink, EIS Spectrum Analyzer, and Plotly) will be applied to gain a comprehensive understanding of the morphological behaviour of the cells. The experimental results of this research are expected to align with previous findings, and a quadratic equation will be derived to predict the body's resistance of the A549 lung cancer cell using mathematical and data analysis approaches. Semarak Ilmu Publishing 2024-03-21 Article PeerReviewed application/pdf en http://irep.iium.edu.my/111614/7/111614_Analysis%20of%20impedance%20based%20sensor%20to%20discover.pdf application/pdf en http://irep.iium.edu.my/111614/13/111614_Analysis%20of%20impedance%20based%20sensor%20to%20discover_Scopus.pdf Rashid, Muhammad Mahbubur and Abd Razak, Mohamad Farhan and Hasan, Tahsin Fuad (2024) Analysis of impedance based sensor to discover the invasive nature of A549 lung cancer cell. Journal of Advanced Research in Applied Sciences and Engineering Technology, 41 (2). pp. 238-255. ISSN 2462-1943 https://semarakilmu.com.my/journals/index.php/applied_sciences_eng_tech/index https://doi.org/10.37934/araset.41.2.238255 |
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TK452 Electric apparatus and materials. Electric circuits. Electric networks Rashid, Muhammad Mahbubur Abd Razak, Mohamad Farhan Hasan, Tahsin Fuad Analysis of impedance based sensor to discover the invasive nature of A549 lung cancer cell |
description |
Numerous studies have been conducted to investigate the effectiveness of impedancebased sensors in detecting the invasive behaviour of cancer cells, specifically through the
use of Electric Cell-substrate Impedance Sensing (ECIS)
methodology. However, the current equivalent circuit models
used to represent the invasive nature of cancer cells have
limitations and inaccuracies, and there has been a lack of utilization of mathematical and data analysis software to better understand the growth and invasive behaviour of these cells. To address these gaps, this research aims to measure the impedance of A549 lung cancer cells, develop a simplified equivalent circuit model, and analyse the results using mathematical and data analysis software. The invasive
behaviour of A549 cells will first be studied through impedance measurements, and then a circuit model will be designed and simulated using software tools to reveal the true invasive nature of these cells. Finally, rigorous mathematical analysis and the use of suitable data analysis software (such as Matlab Powergui and Simulink, EIS Spectrum Analyzer, and Plotly) will be applied to gain a comprehensive understanding of the morphological behaviour of the cells. The experimental results of this research are expected to align with previous findings, and a quadratic equation will be derived to predict the body's resistance of the A549 lung cancer cell using mathematical and data analysis approaches. |
format |
Article |
author |
Rashid, Muhammad Mahbubur Abd Razak, Mohamad Farhan Hasan, Tahsin Fuad |
author_facet |
Rashid, Muhammad Mahbubur Abd Razak, Mohamad Farhan Hasan, Tahsin Fuad |
author_sort |
Rashid, Muhammad Mahbubur |
title |
Analysis of impedance based sensor to discover the invasive nature of A549 lung cancer cell |
title_short |
Analysis of impedance based sensor to discover the invasive nature of A549 lung cancer cell |
title_full |
Analysis of impedance based sensor to discover the invasive nature of A549 lung cancer cell |
title_fullStr |
Analysis of impedance based sensor to discover the invasive nature of A549 lung cancer cell |
title_full_unstemmed |
Analysis of impedance based sensor to discover the invasive nature of A549 lung cancer cell |
title_sort |
analysis of impedance based sensor to discover the invasive nature of a549 lung cancer cell |
publisher |
Semarak Ilmu Publishing |
publishDate |
2024 |
url |
http://irep.iium.edu.my/111614/7/111614_Analysis%20of%20impedance%20based%20sensor%20to%20discover.pdf http://irep.iium.edu.my/111614/13/111614_Analysis%20of%20impedance%20based%20sensor%20to%20discover_Scopus.pdf http://irep.iium.edu.my/111614/ https://semarakilmu.com.my/journals/index.php/applied_sciences_eng_tech/index https://doi.org/10.37934/araset.41.2.238255 |
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13.18916 |