Usnic acid as potential inhibitors of BCL2 and P13K protein through network pharmacology-based analysis, molecular docking and molecular dynamic simulation

• Main Authors: Wong, K.K.V., Roney, Miah, Uddin, Nazim, Imran, Syahrul, Gazali, Ahmad Mahfuz, Zamri, Normaiza, Rullah, Kamal, Mohd Aluwi, Mohd Fadhlizil Fasihi
• Format: Article
• Language: English; English; English
• Published: Taylor & Francis 2023
• Subjects: RS403 Materia Medica-Pharmaceutical Chemistry
• Online Access: http://irep.iium.edu.my/108594/19/108594_Usnic%20acid%20as%20potential%20inhibitors%20of%20BCL2%20and%20P13K.pdf; http://irep.iium.edu.my/108594/20/108594_Usnic%20acid%20as%20potential%20inhibitors%20of%20BCL2%20and%20P13K_Scopus.pdf; http://irep.iium.edu.my/108594/21/108594_Usnic%20acid%20as%20potential%20inhibitors%20of%20BCL2%20and%20P13K_WoS.pdf; http://irep.iium.edu.my/108594/; https://www.tandfonline.com/doi/abs/10.1080/07391102.2023.2178506

Usnic acid (UA) lately piqued the interest of researchers for its extraordinary biological characteristics, including anticancer activity. Here, the mechanism was clarified through network pharmacology, molecular docking and molecular dynamic simulation. Sixteen proteins were selected through networ...