Chemoprevention effects through polyamines modulation induced by Clinacanthus nutans in human lung Adenocarcinoma cells (A549)

• Main Authors: Abdul Ghani, Radiah, Azalan, Maryam Syahidah, Nor Azahan Shah, Azni Masturah, Sujangi, Nur Hikmah, Hassan, Hadijah, Wallace, Heather M.
• Format: Article
• Language: English; English
• Published: Penerbit Universiti Putra Malaysia 2023
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://irep.iium.edu.my/107612/1/107612_Chemoprevention%20effects.pdf; http://irep.iium.edu.my/107612/7/107612_Chemoprevention%20effects_SCOPUS.pdf; http://irep.iium.edu.my/107612/

Introduction: Polyamines involves in cellular proliferation, maintenance and transformation which was discovered to be dysregulated in many types of carcinogenesis by which high intracellular bioavailability represent the promotion of tumour growth, invasion and metastasis. While high polyamines typ...