Influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer
This article presents a numerical simulation model using COMSOL software to study breast thermophysical properties. It analyzes tumor heat at different locations within the breast, records breast surface temperatures, investigates the effects of factors such as blood perfusion, size, depth, and the...
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Multidisciplinary Digital Publishing Institute (MDPI)
2023
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my.iium.irep.1058512023-08-29T03:52:05Z http://irep.iium.edu.my/105851/ Influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer Al Husaini, Mohammed Abdulla Salim Habaebi, Mohamed Hadi Suliman, F. M. Islam, Md. Rafiqul Elsheikh, Elfatih A. A. Muhaisen, Naser A. TK7800 Electronics. Computer engineering. Computer hardware. Photoelectronic devices This article presents a numerical simulation model using COMSOL software to study breast thermophysical properties. It analyzes tumor heat at different locations within the breast, records breast surface temperatures, investigates the effects of factors such as blood perfusion, size, depth, and thermal conductivity on breast size, and applies Pennes’ bioheat formula to illustrate thermal distribution on the breast skin surface. An analysis was conducted to examine how changes in tumor location depth, size, metabolism, blood flow, and heat conductivity affect breast skin surface temperature. The simulation model results showed that the highest variations in skin temperatures for breasts with tumors and without tumors can range from 2.58 °C to 0.274 °C. Further, large breast size with a large surface area consistently reduces the temperature variations on the skin and might have difficulty in yielding observable temperature contrast. For small breast sizes, however, heat from tumor sizes below 0.5 cm might be quite difficult to detect, while tumors located deep within the breast layers could not produce observable temperature variations. Motivated by the above interesting results, an emulation experiment was conducted to enhance the observable heat and temperature background contrast, using situ-cooling gel applied to silicon breasts, while the tumor source was emulated using LEDs. The experiment was used to evaluate the effectiveness of adding situ-cooling to the breast surface area, and to study the modulated effect of tumor size and depth. Experimental results showed that situ-cooling enhances thermal contrast in breast thermal images. For example, for a tumor location at a depth of 10 cm, a difference of 6 °C can still be achieved with situ-cooling gel applied, a feat that was not possible in the simulation model. Furthermore, changes in tumor size and location depth significantly impacted surface temperature distribution. Multidisciplinary Digital Publishing Institute (MDPI) 2023-07-28 Article PeerReviewed application/pdf en http://irep.iium.edu.my/105851/1/105851_Influence%20of%20tissue.pdf application/pdf en http://irep.iium.edu.my/105851/7/105851_Influence%20of%20tissue_SCOPUS.pdf Al Husaini, Mohammed Abdulla Salim and Habaebi, Mohamed Hadi and Suliman, F. M. and Islam, Md. Rafiqul and Elsheikh, Elfatih A. A. and Muhaisen, Naser A. (2023) Influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer. Applied Sciences, 13 (15). pp. 1-36. E-ISSN 2076-3417 https://www.mdpi.com/2076-3417/13/15/8752 10.3390/app13158752 |
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TK7800 Electronics. Computer engineering. Computer hardware. Photoelectronic devices Al Husaini, Mohammed Abdulla Salim Habaebi, Mohamed Hadi Suliman, F. M. Islam, Md. Rafiqul Elsheikh, Elfatih A. A. Muhaisen, Naser A. Influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer |
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This article presents a numerical simulation model using COMSOL software to study breast thermophysical properties. It analyzes tumor heat at different locations within the breast,
records breast surface temperatures, investigates the effects of factors such as blood perfusion, size, depth, and thermal conductivity on breast size, and applies Pennes’ bioheat formula to illustrate thermal distribution on the breast skin surface. An analysis was conducted to examine how changes in tumor location depth, size, metabolism, blood flow, and heat conductivity affect breast skin surface temperature. The simulation model results showed that the highest variations in skin temperatures for breasts with tumors and without tumors can range from 2.58 °C to 0.274 °C. Further, large breast size with a large surface area consistently reduces the temperature variations on the skin and might have difficulty in yielding observable temperature contrast. For small breast sizes, however,
heat from tumor sizes below 0.5 cm might be quite difficult to detect, while tumors located deep within the breast layers could not produce observable temperature variations. Motivated by the
above interesting results, an emulation experiment was conducted to enhance the observable heat and temperature background contrast, using situ-cooling gel applied to silicon breasts, while the tumor source was emulated using LEDs. The experiment was used to evaluate the effectiveness of adding situ-cooling to the breast surface area, and to study the modulated effect of tumor size and depth. Experimental results showed that situ-cooling enhances thermal contrast in breast thermal images. For example, for a tumor location at a depth of 10 cm, a difference of 6 °C can still be achieved with situ-cooling gel applied, a feat that was not possible in the simulation model. Furthermore, changes in tumor size and location depth significantly impacted surface temperature distribution. |
format |
Article |
author |
Al Husaini, Mohammed Abdulla Salim Habaebi, Mohamed Hadi Suliman, F. M. Islam, Md. Rafiqul Elsheikh, Elfatih A. A. Muhaisen, Naser A. |
author_facet |
Al Husaini, Mohammed Abdulla Salim Habaebi, Mohamed Hadi Suliman, F. M. Islam, Md. Rafiqul Elsheikh, Elfatih A. A. Muhaisen, Naser A. |
author_sort |
Al Husaini, Mohammed Abdulla Salim |
title |
Influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer |
title_short |
Influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer |
title_full |
Influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer |
title_fullStr |
Influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer |
title_full_unstemmed |
Influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer |
title_sort |
influence of tissue thermophysical characteristics and situ-cooling on the detection of breast cancer |
publisher |
Multidisciplinary Digital Publishing Institute (MDPI) |
publishDate |
2023 |
url |
http://irep.iium.edu.my/105851/1/105851_Influence%20of%20tissue.pdf http://irep.iium.edu.my/105851/7/105851_Influence%20of%20tissue_SCOPUS.pdf http://irep.iium.edu.my/105851/ https://www.mdpi.com/2076-3417/13/15/8752 |
_version_ |
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13.18916 |