Development of ultraviolet spectroscopic method for the estimation of metronidazole nanoparticles for periodontal disease treatment

• Main Authors: Mohd Zayi, Nora Azirah, Mohamed Halim, Muhammad Lutfi, Harun @ Ismail, Ahmad Fahmi, Mohamad, Mohd Yusof
• Format: Article
• Language: English; English
• Published: Malaysian Journal of Chemistry 2023
• Subjects: QD Chemistry; R Medicine (General); RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
• Online Access: http://irep.iium.edu.my/105536/13/105536_%20Development%20of%20ultraviolet%20spectroscopic%20method.pdf; http://irep.iium.edu.my/105536/19/105536_Development%20of%20ultraviolet%20spectroscopic%20method_Scopus.pdf; http://irep.iium.edu.my/105536/; https://ikm.org.my/publications/malaysian-journal-of-chemistry/view-pdf.php?idx=J0044-db79064; https://doi.org/10.55373/mjchem.v25i3.354

In periodontitis treatment, metronidazole (MT) is applied topically to reduce systemic side effects and reach the target site. treatment of periodontitis via sustained MT release. The UVspectrophotometer analysis was developed and validated to quantify the encapsulated MT according to ICH Q2 (R1) gu...