Sustained blood pressure reduction with chronic 1,2,3,4- tetrahydroisoquinolines administration in young adult, spontaneously hypertensive rats

• Main Authors: Abdullah, Aszrin, Mohd. Shah, Azarisman, Abdul Razak, Tariq, Mohd Noor, Noriah
• Format: Conference or Workshop Item
• Language: English
• Published: 2011
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/10282/1/SUSTAINED_BLOOD_PRESSURE_REDUCTION_WITH_CHRONIC_1.pdf; http://irep.iium.edu.my/10282/; http:// www.msh.my

Background: Adrenaline plays a role in the pathogenesis of essential hypertension through excessive stimulation of the adrenomedullary hormonal system. Pharmacological inhibition of the adrenomedullary hormonal system should result in chronic, sustained blood pressure (BP) reduction. Objective: To...