The role of intra-operative parathyroid hormone assay in non-localized adenoma
The incidence of primary hyperparathyroidism (PHPT) is increasing in trend due to more common practice of routine blood investigations especially in the elderly. Surgery is the only curative therapy in symptomatic patients. We present a case of a 63-year-old lady with generalised body weakness assoc...
Saved in:
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
PROFESSIONAL MEDICAL PUBLICATIONS
2022
|
Subjects: | |
Online Access: | http://irep.iium.edu.my/100181/1/pjms/article/view/5688 http://irep.iium.edu.my/100181/ https://pjms.org.pk/index.php/pjms/article/view/5688/1512 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
my.iium.irep.100181 |
---|---|
record_format |
dspace |
spelling |
my.iium.irep.1001812022-09-26T02:33:41Z http://irep.iium.edu.my/100181/ The role of intra-operative parathyroid hormone assay in non-localized adenoma Mahno, Noor Ezmas Abdul Wahab, Norasyikin Md Latar, Nani Harlina RD Surgery The incidence of primary hyperparathyroidism (PHPT) is increasing in trend due to more common practice of routine blood investigations especially in the elderly. Surgery is the only curative therapy in symptomatic patients. We present a case of a 63-year-old lady with generalised body weakness associated with occasional muscle cramps. Her biochemical results were consistent with PHPT. As a result of persistent severe hypercalcemia, surgery was planned. However, the pre-operative anatomical and functional radiological imaging (neck ultrasonography, 99mTc-MIBI and FDG-PET scans) failed to identify the abnormal parathyroid gland. Therefore, bilateral neck exploration with intra-operative parathyroid hormone (io-PTH) measurement was performed. The nodular left thyroid and adenomatous right superior parathyroid glands were removed. Possible causes of negative localization and incorporation of io-PTH in under-resourced countries to ensure successful surgery are discussed. PROFESSIONAL MEDICAL PUBLICATIONS 2022 Article PeerReviewed application/pdf en cc_by http://irep.iium.edu.my/100181/1/pjms/article/view/5688 Mahno, Noor Ezmas and Abdul Wahab, Norasyikin and Md Latar, Nani Harlina (2022) The role of intra-operative parathyroid hormone assay in non-localized adenoma. Pakistan Journal of Medical Sciences, 38 (8). pp. 1-4. ISSN 1682-024X E-ISSN 1681-715X (In Press) https://pjms.org.pk/index.php/pjms/article/view/5688/1512 10.12669/pjms.38.8.5688 |
institution |
Universiti Islam Antarabangsa Malaysia |
building |
IIUM Library |
collection |
Institutional Repository |
continent |
Asia |
country |
Malaysia |
content_provider |
International Islamic University Malaysia |
content_source |
IIUM Repository (IREP) |
url_provider |
http://irep.iium.edu.my/ |
language |
English |
topic |
RD Surgery |
spellingShingle |
RD Surgery Mahno, Noor Ezmas Abdul Wahab, Norasyikin Md Latar, Nani Harlina The role of intra-operative parathyroid hormone assay in non-localized adenoma |
description |
The incidence of primary hyperparathyroidism (PHPT) is increasing in trend due to more common practice of routine blood investigations especially in the elderly. Surgery is the only curative therapy in symptomatic patients. We present a case of a 63-year-old lady with generalised body weakness associated with occasional muscle cramps. Her biochemical results were consistent with PHPT. As a result of persistent severe hypercalcemia, surgery was planned. However, the pre-operative anatomical and functional radiological imaging (neck ultrasonography, 99mTc-MIBI and FDG-PET scans) failed to identify the abnormal parathyroid gland. Therefore, bilateral neck exploration with intra-operative parathyroid hormone (io-PTH) measurement was performed. The nodular left thyroid and adenomatous right superior parathyroid glands were removed. Possible causes of negative localization and incorporation of io-PTH in under-resourced countries to ensure successful surgery are discussed. |
format |
Article |
author |
Mahno, Noor Ezmas Abdul Wahab, Norasyikin Md Latar, Nani Harlina |
author_facet |
Mahno, Noor Ezmas Abdul Wahab, Norasyikin Md Latar, Nani Harlina |
author_sort |
Mahno, Noor Ezmas |
title |
The role of intra-operative parathyroid hormone assay in non-localized adenoma |
title_short |
The role of intra-operative parathyroid hormone assay in non-localized adenoma |
title_full |
The role of intra-operative parathyroid hormone assay in non-localized adenoma |
title_fullStr |
The role of intra-operative parathyroid hormone assay in non-localized adenoma |
title_full_unstemmed |
The role of intra-operative parathyroid hormone assay in non-localized adenoma |
title_sort |
role of intra-operative parathyroid hormone assay in non-localized adenoma |
publisher |
PROFESSIONAL MEDICAL PUBLICATIONS |
publishDate |
2022 |
url |
http://irep.iium.edu.my/100181/1/pjms/article/view/5688 http://irep.iium.edu.my/100181/ https://pjms.org.pk/index.php/pjms/article/view/5688/1512 |
_version_ |
1745562159116451840 |
score |
13.18916 |