DEVELOPMENT OF THE IONIC LIQUID MODIFIED CHITOSAN-TRIPOLYPHOSPHATE MICROPARTICLES FOR CONTROLLING INSULIN RELEASE

The unstable Chitosan-Tripolyphosphate (CS-TPP) nanoparticles/microparticles (NPs/MPs) results in burst release of Insulin in hydrochloric acid (HCl), while partial or poor solubility of material limits drug release in phosphate buffer saline (PBS).

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Bibliographic Details
Main Author: SAFDAR, RIZWAN
Format: Thesis
Language:English
Published: 2021
Subjects:
Online Access:http://utpedia.utp.edu.my/23122/1/Rizwan%20Safdar_G03279.pdf
http://utpedia.utp.edu.my/23122/
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Description
Summary:The unstable Chitosan-Tripolyphosphate (CS-TPP) nanoparticles/microparticles (NPs/MPs) results in burst release of Insulin in hydrochloric acid (HCl), while partial or poor solubility of material limits drug release in phosphate buffer saline (PBS).