MODELING OF HYALURONIC ACID CONTAINING CURCUMINLOADED POLYLACTIC-CO-GLYCOLIC ACID BIOCONJUGATES FOR TARGETED DELIVERY TO CANCER CELLS
This project investigates the 3D molecular modeling of hyaluronic acid (HA), curcumin, polylactic-co-glycolic acid (PLGA) and polyethylene glycol bis amine (PEG-bis amine) and all the possible conjugated forms between the compounds as bioconjugates for targeted delivery to cancer cells. Modeling...
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| Main Author: | |
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| Format: | Final Year Project |
| Language: | English |
| Published: |
Universiti Teknologi PETRONAS
2011
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| Online Access: | http://utpedia.utp.edu.my/10545/1/2011%20-%20Modeling%20of%20Hyaluronic%20Acid%20Containing%20Curcumin-Loaded%20Polulactic-Co-Glycolic%20Acid%20Bioconj.pdf http://utpedia.utp.edu.my/10545/ |
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| Summary: | This project investigates the 3D molecular modeling of hyaluronic acid (HA),
curcumin, polylactic-co-glycolic acid (PLGA) and polyethylene glycol bis amine
(PEG-bis amine) and all the possible conjugated forms between the compounds as
bioconjugates for targeted delivery to cancer cells. Modeling work had been done
using Discovery Studios 2.5 from Accelrys Inc. USA. The study focuses on targeted
delivery of curcumin to colorectal cancer cells. The generated model will be used in
the studies of drug delivery to cancer cells. |
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