Characterization of voltage-gated sodium channel subtypes expressed in the human rhabdomyosarcoma cell line TE671
The TE671 cell line has been widely used as a model of human medulloblastoma1 . Further analysis showed that its phenotypic and cytogenetic properties were similar to the human muscle RD cell line, hence, TE671 was ascribed as rhabdomyosarcoma rather than medulloblastoma2 . Previous studies show...
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| Main Authors: | , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://eprints.unisza.edu.my/734/1/FH03-FSK-20-41088.pdf http://eprints.unisza.edu.my/734/ |
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| Summary: | The TE671 cell line has been widely used as a model of human medulloblastoma1
. Further
analysis showed that its phenotypic and cytogenetic properties were similar to the human muscle RD cell line,
hence, TE671 was ascribed as rhabdomyosarcoma rather than medulloblastoma2
. Previous studies showed that
TE671 cells exhibited voltage-gating properties, cation selectivity and neurotoxin sensitivity-characteristic of
‘classical’ sodium channels of excitable cell2 |
|---|