Prevalence of Helicobacter pylori infection in Pakistani population

• Main Authors: Atif, Amin Baig, Yasrul Izad, Abu Bakar, Khan, M.U.
• Format: Article
• Language: English
• Published: 2017
• Subjects: R Medicine (General)
• Online Access: http://eprints.unisza.edu.my/5977/1/FH02-FP-18-13167.pdf; http://eprints.unisza.edu.my/5977/

Helicobacter pylori (H Pylori) is the microorganism causes persistent bacterial infection worldwide. It is related to peptic ulcers, gastric ulcers; mucosa associated lymphoid tissue lymphoma and gastric cancers. H. pylori has higher prevalence in developing countries of world. This study was conducted to determine the prevalence of H. pylori infection in general population of Lahore, Pakistan. A cross sectional study was conducted at AL-Razi Health Care Centre, Lahore from January 2015 to January 2017. The serum samples of individuals were estimated for anti H. pylori IgG antibodies by enzyme linked immunosorbent assay (ELISA). Total 1502 individuals with age range from 5 to 86 years were included in this study. Out of these 734 (49%) were males and 768 (51%) were females. The results showed that 853 (57%) out of 1502 subjects were seropositive for H. pylori. The prevalence of H. pylori infection was highest (63%) in middle age (41-60 years) group while lowest (33%) in teens and pre teens (<20 years) group. In young age (20-40) and old age (>60 years) groups, the prevalence of H. pylori was 55% and 60% respectively. It can be concluded that the frequency of H. pylori infection increases with age in Pakistani population. Others factors associated with H. pylori infection are needed to be investigated in future.