Simultaneous detection of multiple polymorphisms in CYP2B6 and OPMR1 by nested PCR: A good approach for patients on methadone

Objective: Cytochrome P450 2B6 (CYP2B6) is involved in the metabolism of several therapeutically important drugs and abused intoxicants including methadone. The preferential binding target for methadone is the μ opioid receptor OPRM1. Various SNPs in CYP2B6 and OPRM1 may contribute to clinical outco...

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Bibliographic Details
Main Authors: Nasir, Mohamad, Ahmad Al-Meman, A.A, Roshaniza, Ismail
Format: Article
Language:English
Published: 2014
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Online Access:http://eprints.unisza.edu.my/5314/1/FH02-FPSK-14-00785.jpg
http://eprints.unisza.edu.my/5314/
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