Simultaneous detection of multiple polymorphisms in CYP2B6 and OPMR1 by nested PCR: A good approach for patients on methadone
Objective: Cytochrome P450 2B6 (CYP2B6) is involved in the metabolism of several therapeutically important drugs and abused intoxicants including methadone. The preferential binding target for methadone is the μ opioid receptor OPRM1. Various SNPs in CYP2B6 and OPRM1 may contribute to clinical outco...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | http://eprints.unisza.edu.my/5314/1/FH02-FPSK-14-00785.jpg http://eprints.unisza.edu.my/5314/ |
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