Correlation of Serum Erythropoietin and Ferritin Levels with the Frequency of Blood Donation
Aim: The objective is to assess the correlation of serum ferritin and erythropoietin levels with the frequency of donation among blood donors in Pulau Penang, Malaysia. Methods: One hundred and forty-seven (108 male and 39 female) voluntary whole blood donors whom donating blood at the Blood bank,...
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my-unisza-ir.48582022-01-25T04:14:22Z http://eprints.unisza.edu.my/4858/ Correlation of Serum Erythropoietin and Ferritin Levels with the Frequency of Blood Donation Uday Younis, Hussein Fouz AA, Abdul Aziz Norhaza, A Rahim R Medicine (General) RB Pathology Aim: The objective is to assess the correlation of serum ferritin and erythropoietin levels with the frequency of donation among blood donors in Pulau Penang, Malaysia. Methods: One hundred and forty-seven (108 male and 39 female) voluntary whole blood donors whom donating blood at the Blood bank, Hospital Pulau Pinang were included. For each donor, haemoglobin, serum ferritin and erythropoietin (EPO) assay were done. Laboratory works had been done at the Advanced Diagnostic Laboratories (ADL), Advanced Medical and Dental Institute (AMDI), Universiti Sains Malaysia (USM). Results: A significantly increased (p=0.014) serum ferritin was found in the first time donor (105.3 ng/ml) compared to regular donors (69.3 ng/ml) who had donate blood more than once in the preceding year of both gender. The larger amount of donated blood in regular male donor results in a more risk of latent iron deficiency compared to female counterpart. EPO was significantly higher while ferritin was significantly lower in regular donors than in the control. The serum EPO showed a statistically significant inverse relationship with ferritin level and this relationship was significantly correlated. Conclusion: Adequate daily, oral iron supplementation at post donation would need to be provided for 90 days, which is longer than most current recommended iron replenishment programs together with the introduction of serum ferritin assay at first donation and annually for regular donors to increase the safety of national blood supply recommended. Article PeerReviewed text en http://eprints.unisza.edu.my/4858/1/FH02-FP-15-03066.pdf Uday Younis, Hussein and Fouz AA, Abdul Aziz and Norhaza, A Rahim Correlation of Serum Erythropoietin and Ferritin Levels with the Frequency of Blood Donation. Journal of Blood Disorders and Transfusion, 5 (8). pp. 1-4. ISSN 2155-9864 http://dx.doi.org/10.4172/2155-9864.1000232 |
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R Medicine (General) RB Pathology Uday Younis, Hussein Fouz AA, Abdul Aziz Norhaza, A Rahim Correlation of Serum Erythropoietin and Ferritin Levels with the Frequency of Blood Donation |
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Aim: The objective is to assess the correlation of serum ferritin and erythropoietin levels with the frequency of
donation among blood donors in Pulau Penang, Malaysia. Methods: One hundred and forty-seven (108 male and
39 female) voluntary whole blood donors whom donating blood at the Blood bank, Hospital Pulau Pinang were
included. For each donor, haemoglobin, serum ferritin and erythropoietin (EPO) assay were done. Laboratory
works had been done at the Advanced Diagnostic Laboratories (ADL), Advanced Medical and Dental Institute
(AMDI), Universiti Sains Malaysia (USM).
Results: A significantly increased (p=0.014) serum ferritin was found in the first time donor (105.3 ng/ml)
compared to regular donors (69.3 ng/ml) who had donate blood more than once in the preceding year of both
gender. The larger amount of donated blood in regular male donor results in a more risk of latent iron deficiency
compared to female counterpart. EPO was significantly higher while ferritin was significantly lower in regular
donors than in the control. The serum EPO showed a statistically significant inverse relationship with ferritin level
and this relationship was significantly correlated.
Conclusion: Adequate daily, oral iron supplementation at post donation would need to be provided for 90
days, which is longer than most current recommended iron replenishment programs together with the introduction
of serum ferritin assay at first donation and annually for regular donors to increase the safety of national blood
supply recommended. |
format |
Article |
author |
Uday Younis, Hussein Fouz AA, Abdul Aziz Norhaza, A Rahim |
author_facet |
Uday Younis, Hussein Fouz AA, Abdul Aziz Norhaza, A Rahim |
author_sort |
Uday Younis, Hussein |
title |
Correlation of Serum Erythropoietin and Ferritin Levels with the Frequency of Blood Donation |
title_short |
Correlation of Serum Erythropoietin and Ferritin Levels with the Frequency of Blood Donation |
title_full |
Correlation of Serum Erythropoietin and Ferritin Levels with the Frequency of Blood Donation |
title_fullStr |
Correlation of Serum Erythropoietin and Ferritin Levels with the Frequency of Blood Donation |
title_full_unstemmed |
Correlation of Serum Erythropoietin and Ferritin Levels with the Frequency of Blood Donation |
title_sort |
correlation of serum erythropoietin and ferritin levels with the frequency of blood donation |
url |
http://eprints.unisza.edu.my/4858/1/FH02-FP-15-03066.pdf http://eprints.unisza.edu.my/4858/ http://dx.doi.org/10.4172/2155-9864.1000232 |
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