Lower Erythrocyte GST activity in Autism Spectrum Disorder (ASD) patients compared to normal controls

• Main Authors: Donna Hermawati,, Then, Sue-Mian, Tri Indah Winarni,, Sultana MH Faradz,, Rahman Jamal,
• Format: Article
• Language: English
• Published: UKM Medical Molecular biology Institute, UMBI 2011
• Online Access: http://journalarticle.ukm.my/3062/1/2011-1-2.pdf; http://journalarticle.ukm.my/3062/; http://www.umbi.ukm.my/umbi/index.php?option=com_content&task=view&id=388&Itemid=72

Glutathione S-transferases (GST) are antioxidant enzymes that play an important role in the cellular detoxification and excretion of environmental pollutants including heavy metals. GST mu (GSTM1) and G theta (GSTT1) are known to be highly polymorphic and homozygous deletions of these genes result...