Virulence gene typing of Methicillin-susceptible Staphylococcus aureus (MSSA)isolates in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)

• Main Authors: Hassriana Fazilla Sapri,, Nurul Azirah Mohamad Sani,, Ainihayati Noordin,, Hui-min Neoh,, Salasawati Hussin,
• Format: Article
• Language: English
• Published: UKM Medical Molecular biology Institute, UMBI 2011
• Online Access: http://journalarticle.ukm.my/3060/1/2011-1-4.pdf; http://journalarticle.ukm.my/3060/; http://www.umbi.ukm.my/umbi/index.php?option=com_content&task=view&id=388&Itemid=72

We determined the presence of four virulence genes: (cna, seh, PVL, TSST-1) using multiplex PCR in 880 isolates of methicillin-susceptible Staphylococcus aureus (MSSA) collected from the Universiti Kebangsaan Malaysia Medical Centre (UKMMC) in 2009. We found that 51.59% (454/880) of the strains had cna; 21.82% (192/880) possessed seh; 10.23% (90/880) had PVL and 6.82% (60/880) haboured TSST-1. Although methicillin-susceptible, MSSA carries important virulence genes which could affect patient’s clinical course.