From Zebrafish to humans: in silico comparative study of RAD50 sequences

• المؤلفون الرئيسيون: Nahid Khalili,, Ahmed Najm,, Mahmood, Ibrahim, Douglas, Law, Chyan, Leong Ng, Ahmad Azfaralariff,, Shazrul Fazry,
• التنسيق: مقال
• اللغة: English
• منشور في: Penerbit Universiti Kebangsaan Malaysia 2024
• الوصول للمادة أونلاين: http://journalarticle.ukm.my/24768/1/MAE%2017.pdf; http://journalarticle.ukm.my/24768/; https://jms.mabjournal.com/index.php/mab/issue/view/63

DNA damage, particularly the occurrence of DNA double-strand breaks (DSBs), presents a significant hazard to the integrity and viability of cells. Improper repair of DSBs can result in chromosomal alterations, oncogenic changes, or cell demise. The MRE11-RAD50-NBS1 (MRN) complex plays a crucial role...