Design and characterisation of curcumin-loaded nanostructured lipid carriers for safe and efficient topical drug delivery in the treatment of pressure ulcer

• Main Authors: Nur Amira Mohd Shamsuddin,, Fazren Azmi,, Khairana Husain,, Leong, Lek Mun, Mohd Hanif Zulfakar,
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2024
• Online Access: http://journalarticle.ukm.my/24124/1/SME%2010.pdf; http://journalarticle.ukm.my/24124/; https://www.ukm.my/jsm/english_journals/vol53num6_2024/contentsVol53num6_2024.html

Pressure ulcers (PU) are chronic lesions with a high prevalence in at-risk populations. Although curcumin has various therapeutic properties, its use as a dermal therapeutic agent is limited by its poor solubility and permeability. This study aimed to develop nanostructured lipid carriers (NLCs) to...