In silico design and evaluation of novel cell targeting melittin-interleukin-24 fusion protein: a potential drug candidate against breast cancer

• Main Authors: Rehman, Hafiz Muhammad, Rehman, Hafiz Muzzammel, Ahmed, Nadeem, Amirzada, Muhammad Imran, Aslam, Shakira, Bashir, Hamid
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2023
• Online Access: http://journalarticle.ukm.my/23251/1/SB%2015.pdf; http://journalarticle.ukm.my/23251/; https://www.ukm.my/jsm/english_journals/vol52num11_2023/contentsVol52num11_2023.html

Fusion proteins are designed to achieve new functionality or improved properties synergistically by incorporating multiple protein domains into one complex. The fusion of two genes to translate a recombinant protein for cancer treatment can enhance the bioactivity of drug and can introduce novel dru...