Physicochemical and pharmacokinetic evaluation of praziquantel co-crystals by varying the spacer group of co-crystal formers

• Main Authors: Muhammad Wasim,, Abdul Mannan,, Azim, Tabinda, Ali Khan, Rashid, Alotaibi, Ghallab, Muhammad Amer,, Muhammad Shafique,, Muhammad Asghar Khan,, Gul, Sumaira, Hussain, Izhar
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2022
• Online Access: http://journalarticle.ukm.my/20871/1/13.pdf; http://journalarticle.ukm.my/20871/; https://www.ukm.my/jsm/malay_journals/jilid51bil10_2022/KandunganJilid51Bil10_2022.html

The research work focuses on investigating the effects of spacer group (varying aliphatic chain length=n) of co-crystal formers (oxalic acid (OA, n=0), (malonic acid (MA, n=1), (succinic acid (SA, n=2), (glutaric acid (GA, n=3), and (adipic acid (AA, n=4) on the physicochemical properties and or...