Understanding the tuberculosis disease progression and future directions of research in tuberculosis : a mini review
Eradication of tuberculosis seems to be a long way off especially with the growing of drug resistance tuberculosis and HIV co-infection tuberculosis. The gaps in our knowledge and the limited sensitive and specific biomarkers especially for latent tuberculosis infection make it defensive. The fat...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pusat Perubatan Universiti Kebangsaan Malaysia
2018
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| Online Access: | http://journalarticle.ukm.my/20197/1/4_ms392_pdf_48261.pdf http://journalarticle.ukm.my/20197/ https://www.medicineandhealthukm.com/toc/13/1 |
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| Summary: | Eradication of tuberculosis seems to be a long way off especially with the growing
of drug resistance tuberculosis and HIV co-infection tuberculosis. The gaps in
our knowledge and the limited sensitive and specific biomarkers especially for
latent tuberculosis infection make it defensive. The fate of tuberculosis treatmentranged from cured to failure and there are many risk factors involved apart from
the immune state and age. Therefore, this review focuses on the understanding
of tuberculosis disease progression and the associated risk factors of the events in
the disease progression. This article also highlights the diagnostic and predictive
marker that may predict the disease progression. In addition, this review highlights
the potential use of rifabutin in tuberculosis treatment regimen. It is hoped that this
review could give an overview on future directions of research in tuberculosis. |
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