(+)-Neocadambine A and (-)-nauclederine isolated from the bark of Neolamarckia cadamba (Rubiaceae) as natural advanced glycation end products (AGEs) inhibitors

• Main Authors: Noor Aimi Othman,, Liew, Sook Yee, Blanchard, Patricia, Derbré, Séverine, Chong, Soon-Lim, Abdul Manaf Ali,, Khalijah Awang,
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2022
• Online Access: http://journalarticle.ukm.my/19747/1/10.pdf; http://journalarticle.ukm.my/19747/; https://www.ukm.my/jsm/malay_journals/jilid51bil6_2022/KandunganJilid51Bil6_2022.html

The phytochemical study on the dichloromethane extract of Neolamarckia cadamba (Roxb.) Bosser has afforded two indole alkaloids, (+)-neocadambine A (1) and (-)-nauclederine (2). Their structures were confirmed by extensive spectroscopic analysis and by comparing with the reported data. (+)-Neocadamb...