Effects of age and tocotrienol-rich fraction on mitochondrial respiratory complexes in the hippocampus of rats

• Main Authors: Tan, Jen Kit, Sakinah Husna Abdul Razak,, Nazirah Ab Rani,, Nur Haleeda Hakimi,, Hanafi Ahmad Damanhuri,, Suzana Makpol,, Wan Zurinah Wan Ngah,
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2022
• Online Access: http://journalarticle.ukm.my/18362/1/20.pdf; http://journalarticle.ukm.my/18362/; https://www.ukm.my/jsm/malay_journals/jilid51bil1_2022/KandunganJilid51Bil1_2022.html

Mitochondrial dysfunction is common in the brain with age. Prevention of mitochondrial dysfunction at an early age may protect the brain against neurodegeneration in later life. Tocotrienol-rich fraction (TRF) has been reported to be neuroprotective in old rats, but its effect remains unknown for mi...