Detection of BCR/ABL gene in chronic Myeloid Leukaemia: comparison of Fluorescence in situ Hybridisation (FISH), conventional Cytogenetics and Polymerase Chain Reaction (PCR) techniques

The reciprocal translocation t(9;22)(q34;q11) which gives rise to the Philadelphia (Ph1) chromosome and BCR/ABL fusion gene, plays a pivotal role in the diagnosis and pathogenesis of chronic myeloid leukemia (CML). In this study, we evaluated the role of fluorescence in situ hybridisation (FISH) in...

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Bibliographic Details
Main Authors: Reena RMZ,, Julia Munchar MJ,, Salwati S,,, Hamidah NH,, Zubaidah Z,, Sharifah NA,, Cheong SK,
Format: Article
Language:English
Published: Penerbit UKM 2006
Online Access:http://journalarticle.ukm.my/1829/1/02._5-13_%28MH_006%29.pdf
http://journalarticle.ukm.my/1829/
http://www.ppukm.ukm.my/ukmmcjournal/index.php
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