A comparative study of microwave-assisted and conventional heating methods of the synthesis of 1-(Naphthalene-1-Yl)-3-(O, M, P-Tolyl)thioureas, DFT analysis, antibacterial evaluation and drug-likeness assessment

• Main Authors: Suhaila Sapari,, Emma Izzati Zakariah,, Nurul Hidayah Abdul Razak,, Insyirah Ramzan,, Mohd Sofi Numin,, Lee, Yook Heng, Siti Aishah Hasbullah,
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2021
• Online Access: http://journalarticle.ukm.my/16914/1/16.pdf; http://journalarticle.ukm.my/16914/; https://www.ukm.my/jsm/malay_journals/jilid50bil3_2021/KandunganJilid50Bil3_2021.html

New isomers of naphthalene-monothioureas, 3a-3c, were synthesized and characterized by using infrared (IR), 1 H and 13 C nuclear magnetic resonance (NMR) and mass spectroscopies (MS). The compounds were obtained from the reaction of o-, m-, p- toluidine with naphthyl isothiocyanate using conven...