Formulation of metformin-loaded alginate microspheres by ionotropic gelationaerosolization technique

• Main Authors: Hariyadi, Dewi Melani, Pathak, Yashwant, Hendradi, Esti, Erawati, Tristiana, Izzatul Hidayah,, Santoso, Elizabeth
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2020
• Online Access: http://journalarticle.ukm.my/15947/1/17.pdf; http://journalarticle.ukm.my/15947/; http://www.ukm.my/jsm/malay_journals/jilid49bil10_2020/KandunganJilid49Bil10_2020.html

Metformin hydrochloric acid (HCl)-loaded alginate microspheres prepared using aerosolization method were subsequently evaluated for their physico-chemical characteristics in terms of particle size, morphology, drug loading, entrapment efficiency, yield and in vitro release. A two factorial Design...