Role of novel therapeutic agents in modulating invadopodia formation in metastatic breast cancer

• Main Authors: Siti Nor Aini Harun,, Nurul Akmaryanti Abdullah,, Noraina Muhamad Zakuan,, Hafizah Abdul Hamid,, Muhammad Zulfadli Mehat,, Nur Fariesha Md Hashim,
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2020
• Online Access: http://journalarticle.ukm.my/15470/1/13.pdf; http://journalarticle.ukm.my/15470/; http://www.ukm.my/jsm/malay_journals/jilid49bil6_2020/KandunganJilid49Bil6_2020.html

The ability to colonize distant organs which is lethal has made metastatic breast cancer become the top ten causes of mortality worldwide. Specialized actin-rich protrusions termed invadopodia were thought to be formed by highly invasive cells to degrade the extracellular matrix to drive cancer in...