The effect of different concentrations of calcium silicate-maghemite coating towards magnetic behavior and bioactivity

• Main Authors: Nor Hazirah Mohd Akhirudin,, Roslinda Shamsudin,, Norinsan Kamil Othman,
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2020
• Online Access: http://journalarticle.ukm.my/15196/1/ARTIKEL%2020.pdf; http://journalarticle.ukm.my/15196/; http://www.ukm.my/jsm/malay_journals/jilid49bil3_2020/KandunganJilid49Bil3_2020.html

In this study, maghemite (γ-Fe2O3) as magnetic nanoparticles (MNPs) material was coated by ceramic materials, calcium silicate (CaSiO3) with different concentrations to suit the medical treatment needed. Different concentration was studied to assess the optimal parameter and ability to maintain post-coated superparamagnetic properties of γ-Fe2O3. Concentration of CaSiO3 coated on γ-Fe2O3 was prepared with 3 parameters, 97:3, 95:5, and 93:7% w/w, respectively. Magnetic properties of CaSiO3-γ-Fe2O3 were characterized by VSM proceeded with a bioactive study analyzed with FESEM and FTIR after simulated body fluid immersion for 5 days at 37±1ºC. CaSiO3-γ-Fe2O3 with concentration 95:5% w/w exhibit the highest magnetization makes it the most optimum with the average coercivity is 1.6G. FESEM analysis illustrates that the existence of the apatite layer after 5 days of simulated body fluid (SBF) immersion on CaSiO3-γ-Fe2O3 coating sample, which confirmed the bioactive properties. Therefore, CaSiO3-γ-Fe2O3 concentration at ratio 95:5% w/w can be a promising new biomaterial candidate to be applied in the medical field.