Human platelet lysate promotes proliferation but fails to maintain chondrogenic markers of chondrocytes

• Main Authors: Prana Hardinata Budi Harto,, Muhammad Hanif Mahmud,, Aisya Hanim Othman,, Nurulain Hanani Ngadenin,, Nur Saihah Mohd Azahar,, Muhammad Najib Fathi Hassan,, Nor Hamdan Mohd Yahaya,, Rizal Abdul Rani,, Leong, Chooi Fun, Ng, Min Hwei, Law, Jia Xian
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2019
• Online Access: http://journalarticle.ukm.my/14389/1/12%20Prana%20Hardinata.pdf; http://journalarticle.ukm.my/14389/; http://www.ukm.my/jsm/malay_journals/jilid48bil10_2019/KandunganJilid48Bil10_2019.htm

Traditionally, foetal bovine serum (FBS) is used as a serum supplement for stem cell expansion in vitro. However, it is associated with xenoimmunisation and the transmission of animal pathogens, which may cause harm to stem cell recipients. As a safer alternative, human platelet lysate (HPL) has bee...