Polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications

Simple, facile and cost effective approach is used for the synthesis of Aspirin based silver oxide nano-particles (SONPs) by chemical wet method. The synthesized SONPs were loaded with Aspirin to form Asp-SONPs, which was confirmed with the help of UV spectroscopy. Characterization was done using sp...

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Main Authors: Ahmad, Shabir, Rashid, Hira, Jalil, Qudisa, Munir, Sidra, Barkatullah,, Khan, Sulaiman, Ullah, Riaz, Shahat, Abdelaaty A., M. Mahmood, Hafiz, A-Mishari, Almoqbil A. Naser AbdullahAlmoqbil A. Naser Abdullah, Bari, Ahmad
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2019
Online Access:http://journalarticle.ukm.my/14342/1/09%20Shabir%20Ahmad.pdf
http://journalarticle.ukm.my/14342/
http://www.ukm.my/jsm/malay_journals/jilid48bil9_2019/KandunganJilid48Bil9_2019.html
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spelling my-ukm.journal.143422020-03-03T07:59:14Z http://journalarticle.ukm.my/14342/ Polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications Ahmad, Shabir Rashid, Hira Jalil, Qudisa Munir, Sidra Barkatullah, Khan, Sulaiman Ullah, Riaz Shahat, Abdelaaty A. M. Mahmood, Hafiz A-Mishari, Almoqbil A. Naser AbdullahAlmoqbil A. Naser Abdullah Bari, Ahmad Simple, facile and cost effective approach is used for the synthesis of Aspirin based silver oxide nano-particles (SONPs) by chemical wet method. The synthesized SONPs were loaded with Aspirin to form Asp-SONPs, which was confirmed with the help of UV spectroscopy. Characterization was done using spectroscopy techniques FTIR, SEM, TEM and XRD. Antimicrobial assay of Asp-SONPs were carried out against six bacterial strains (E. coli, Protues, Vibrio, Citrobacter, Enterobacter, S. aureus) and fungal strains (Curvularia, Alternaria, Rhizopus, Aspergillus, Helmithosporium, Paecilomyces) by well diffusion method which confirmed its potential application as an antimicrobial agent. Asp-SONPs-PVA also displayed highest insecticidal activity against both tested insects (Tribolium casterium and Callosobruchus chinensis) having LC50 value of 15.917, and 37.6365 and highest percent mortality at 1000 ppm was 67%, and 73%, respectively. PVA coated SONPs displayed encouraging phytotoxicity when exposed to allopathic, where Asp-SONPs coated PVA give excellent anthelmintic activity by killing or paralyzing all the species (earthworm) at 1000 ppm. Penerbit Universiti Kebangsaan Malaysia 2019-09 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/14342/1/09%20Shabir%20Ahmad.pdf Ahmad, Shabir and Rashid, Hira and Jalil, Qudisa and Munir, Sidra and Barkatullah, and Khan, Sulaiman and Ullah, Riaz and Shahat, Abdelaaty A. and M. Mahmood, Hafiz and A-Mishari, Almoqbil A. Naser AbdullahAlmoqbil A. Naser Abdullah and Bari, Ahmad (2019) Polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications. Sains Malaysiana, 48 (9). pp. 1887-1897. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid48bil9_2019/KandunganJilid48Bil9_2019.html
institution Universiti Kebangsaan Malaysia
building Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Simple, facile and cost effective approach is used for the synthesis of Aspirin based silver oxide nano-particles (SONPs) by chemical wet method. The synthesized SONPs were loaded with Aspirin to form Asp-SONPs, which was confirmed with the help of UV spectroscopy. Characterization was done using spectroscopy techniques FTIR, SEM, TEM and XRD. Antimicrobial assay of Asp-SONPs were carried out against six bacterial strains (E. coli, Protues, Vibrio, Citrobacter, Enterobacter, S. aureus) and fungal strains (Curvularia, Alternaria, Rhizopus, Aspergillus, Helmithosporium, Paecilomyces) by well diffusion method which confirmed its potential application as an antimicrobial agent. Asp-SONPs-PVA also displayed highest insecticidal activity against both tested insects (Tribolium casterium and Callosobruchus chinensis) having LC50 value of 15.917, and 37.6365 and highest percent mortality at 1000 ppm was 67%, and 73%, respectively. PVA coated SONPs displayed encouraging phytotoxicity when exposed to allopathic, where Asp-SONPs coated PVA give excellent anthelmintic activity by killing or paralyzing all the species (earthworm) at 1000 ppm.
format Article
author Ahmad, Shabir
Rashid, Hira
Jalil, Qudisa
Munir, Sidra
Barkatullah,
Khan, Sulaiman
Ullah, Riaz
Shahat, Abdelaaty A.
M. Mahmood, Hafiz
A-Mishari, Almoqbil A. Naser AbdullahAlmoqbil A. Naser Abdullah
Bari, Ahmad
spellingShingle Ahmad, Shabir
Rashid, Hira
Jalil, Qudisa
Munir, Sidra
Barkatullah,
Khan, Sulaiman
Ullah, Riaz
Shahat, Abdelaaty A.
M. Mahmood, Hafiz
A-Mishari, Almoqbil A. Naser AbdullahAlmoqbil A. Naser Abdullah
Bari, Ahmad
Polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications
author_facet Ahmad, Shabir
Rashid, Hira
Jalil, Qudisa
Munir, Sidra
Barkatullah,
Khan, Sulaiman
Ullah, Riaz
Shahat, Abdelaaty A.
M. Mahmood, Hafiz
A-Mishari, Almoqbil A. Naser AbdullahAlmoqbil A. Naser Abdullah
Bari, Ahmad
author_sort Ahmad, Shabir
title Polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications
title_short Polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications
title_full Polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications
title_fullStr Polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications
title_full_unstemmed Polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications
title_sort polymers encapsulated aspirin loaded silver oxide nanoparticles: synthesis, characterization and its bio-applications
publisher Penerbit Universiti Kebangsaan Malaysia
publishDate 2019
url http://journalarticle.ukm.my/14342/1/09%20Shabir%20Ahmad.pdf
http://journalarticle.ukm.my/14342/
http://www.ukm.my/jsm/malay_journals/jilid48bil9_2019/KandunganJilid48Bil9_2019.html
_version_ 1662755955952058368
score 13.209306