An in vitro three-dimensional co-culture system for ameloblastoma modelling

• Main Authors: Lee, Soo Leng, Zainal Ariff Abdul Rahman,, Tsujigiwa, Hidetsugu, Hamada, Mei, Takabatake, Kiyofumi, Nakano, Keisuke, Nagatsuka, Hitoshi, Chong, Huat Siar
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2019
• Online Access: http://journalarticle.ukm.my/13892/1/15%20Soo%20Leng%20Lee.pdf; http://journalarticle.ukm.my/13892/; http://www.ukm.my/jsm/malay_journals/jilid48bil8_2019/KandunganJilid48Bil8_2019.html

Ameloblastoma, the most clinically significant odontogenic epithelial tumor, is a locally-invasive and destructive lesion in the jawbones. However, the nature of this infiltrativeness and destructive behavior remains ill-understood. To address this, we established an in vitro three-dimensional (3D)...