Epigenome-wide DNA methylation profiling in colorectal cancer and normal adjacent colon using Infinium human methylation 450K

The aims were to profile the DNA methylation in colorectal cancer (CRC) and to explore cancer-specific methylation biomarkers. Fifty-four pairs of CRCs and the adjacent normal tissues were subjected to Infinium Human Methylation 450K assay and analysed using ChAMP R package. A total of 26,093 differ...

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Main Authors:	Rashidah Baharudin, Muhiddin Ishak, Azliana Muhamad Yusof, Sazuita Saidin, Saiful Effendi Syafruddin, Wan Fahmi Wan Mohamad Nazarie, Lee, Learn-Han, Nurul-Syakima Ab Mutalib
Format:	Article
Language:	en
Published:	MDPI 2022
Subjects:	Q1-390 Science (General) RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
Online Access:	https://eprints.ums.edu.my/id/eprint/42419/1/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/42419/ https://doi.org/10.3390/diagnostics12010198
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