Design and Synthesis of Chalcone Derivatives as Potent Tyrosinase Inhibitors and Their Structural Activity Relationship

Browning of fruits and vegetables is a serious issue in the food industry, as it damages the organoleptic properties of the final products. Overproduction of melanin causes aesthetic problems such as melisma, freckles and lentigo. In this study, a series of chalcones (1-10) have been synthesized and...

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Bibliographic Details
Main Authors: Akhtar, Muhammad Nadeem, Seema, Zareen, Nurshafika, Sakeh, Gul, Sana, Syed Adnan, Ali Shah, Syahida, Ahmad
Format: Article
Language:en
Published: Elsevier Ltd 2015
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Online Access:http://umpir.ump.edu.my/id/eprint/8033/1/fist-2015-nadeem-Design%20and%20synthesis%20of%20chalcone%20derivative1.pdf
http://umpir.ump.edu.my/id/eprint/8033/
http://dx.doi.org/10.1016/j.molstruc.2014.12.073
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