Nrf2-dependent and-independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative stress
Nrf2, an NF-E2-related transcription factor, plays a critical role in transcriptional upregulation of many target genes, including those for metabolizing enzymes and transporters essential for cellular defense in response to oxidative and/or electrophilic stress. In the present study, we have studie...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Published: |
2007
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/5083/ |
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