Polymorphisms in the host CYP2C19 gene and antibiotic-resistance attributes of Helicobacter pylori isolates influence the outcome of triple therapy

Objectives: Eradication of Helicobacter pylori is influenced by susceptibility to antimicrobial agents, elevated bacterial load and degree of acid inhibition, which can be affected by genotypes of drug-metabolizing enzymes [cytochrome P450 (CYP) 2C19 polymorphism]. Theoretically, the choice and dose...

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Main Authors:	Ram M., Ravishankar, Teh, Xinsheng, Rajakumar, Tamayanthi, Goh, Khean Lee, Leow, Alex Hwong Ruey, Poh, Bee Hoon, Mariappan, Vanitha, Shankar, Esaki Muthu, Loke, Mun Fai, Vadivelu, Jamuna
Format:	Article
Published:	Oxford University Press 2018
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/20006/ https://doi.org/10.1093/jac/dky401
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