Molecular dynamics simulations reveal the inhibitory mechanism of Withanolide A against α-glucosidase and α-amylase

Diabetes mellitus (DM) is a global chronic disease characterized by hyperglycemia and insulin resistance. The unsavory severe gastrointestinal side-effects of synthetic drugs to regulate hyperglycemia have warranted the search for alternative treatments to inhibit the carbohydrate digestive enzymes...

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Main Authors: Oyewusi, Habeebat Adekilekun, Wu, Yuan Seng *, Safi, Sher Zaman, Roswanira, Abdul Wahab, Mohd Hayrie, Mohd Hatta, Kalaivani, Batumalaie
Format: Article
Published: Taylor and Francis Group 2023
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Online Access:http://eprints.sunway.edu.my/2881/
https://doi.org/10.1080/07391102.2022.2104375
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